Brads particular restoration focus is with The American Chestnut Foundation, working to develop a disease-resistant American chestnut tree to restore to the Appalachian forest. in Biochemistry from Stony Brook University of New York. Something with a very different immune system and incomplete in fundamental waysperhaps not viable. 1:00 PM 3:15 PM: Biodiversity & Conservation. TED Conferences, LLC.
Currently Ben is working on publications of the worlds first successfully cloned Pzrewalskis horse and black-footed ferret, and a review of the historic trends of cloning research for conservation. Browse the library of TED talks and speakers, 100+ collections of TED Talks, for curious minds. Edge.org is a nonprofit private operating foundation under Section 501(c)(3) of the Internal Revenue Code. Thank you! They would darken the sky. There is concern both that The American chestnut, for example, will not survive without intervention and that using genetics to avert this is nevertheless unwarranted. From genetic technology to NFTs, six speakers give insights on whats to come, celebrate the fusion of tech and human creativity and make the case for rousing the techno-optimist in us all. They say that these flocks were so thick in the sky that when they passed it could take a mile for a flock of birds to go by. They are always seductive. Hunters ate this goat to extinction. One of the fundamental questions here is, is extinction a good thing? Over the last seven years I've been working primarily in personalized medicine, keeping my eye on the application of genomic medicine in different areas, and the growth of genomics and the shockingly drop in the sequencing price, and the cost of sequencing, and what that means to all different areas of science. The way it would work (and again, I'm not the scientist here, George is better to explain it) the idea would be to take the most closely related extant living species and actually compare it genomically with the extinct species, and basically gene by gene match it, and edit it accordingly. This has resulted in the birth of "Elizabeth Ann" the first cloned US endangered species. We are looking for someone who can help us change the current conservation narrative from one based on fear to one filled with thoughtfully planned Intended Consequences to save endangered species. Any individual or organization (local, national, regional, or global) is invited to become a member provided you commit to a significant (for you) commitment to advance the vision and call to action of The Island-Ocean Connection Challenge. An estimated 869 species have gone officially and, so far, irreversibly extinct just since the 16th century, and 290 more species are considered critically endangered and possibly extinct -- and in almost all cases the finger points to humans. We'll be talking with these scientists about the different technologies that they're deploying, of which this genome hybridization technique that George is doing is going to be one and I'm sure there are others. Recently, in an effort to inspire environmentalists to follow science instead of ideology, Stewart wrote Whole Earth Discipline: The Rise of Ecopragmatism (2010, Penguin). University Cultural Centre, 50 Kent Ridge Crescent, National University of Singapore, 119279, Executive director, Cofounder - Revive & Restore. Ryan Phelan is Co-founder and Executive Director of Revive & Restore, a California-based nonprofit with a mission to enhance biodiversity through the genetic rescue of endangered and extinct species. A hundred and fifty years ago the passenger pigeon darkened the sky when it would pass. bridget(at)reviverestore.org @Hey_Bridget_Hey. A species that could eat people? In 2015 Brand was one of the authors of an influential essay, An Ecomodernist Manifesto. He also co-founded The WELL and Global Business Network. and a B.Sc.E. Ryan is a serial entrepreneur, active in both the for-profit and nonprofit worlds. It's one thing to actually bring back a species in the lab. Are we responsible for what we do not do as much as for what we do do? With cofounder Stewart Brand, Phelan made the case for de-extinction at TEDxDeExtinction in 2013, which helped shift perceptions and attitudes about what's possible in a traditionally conservative field. In other words, does this technical solution, which is elegant and scientifically interesting, as Phelan points out, distract from old boring problems? Brand and Phelan seek to restore extinct species to their former homes in the wild. Develop a central repository for standardizing, compiling, consolidating, and analyzing conservation impact monitoring data from island-marine restoration projects worldwide. Ben is now continuing the work he began at CSIRO in the U.S.as a private venture. Ryan works with some of the worlds leading molecular biologists, conservation biologists, and conservation organizations to envision and develop pioneering genetic rescue projects using cutting-edge genomic technologies to solve seemingly intractable wildlife conservation challenges such as those posed by inbreeding, exotic diseases, climate change, and destructive invasive species. Its much worse than that. Basically, what they do is they start by taking the strains of cattle that are closest to the ancient aurochs and try to breed back in much the way they do with plant biology and hybridization. How does it benefit society? Before co-cofounding Saint Partners LLC, Barnaby was a senior executive at the John Templeton Foundation, where he led grantmaking, communications, and philanthropic partnerships.
Through competitive funding processes, he has helped to create new scholarly networks in diverse areas including positive psychology, neuroscience, evolutionary biology, genetics, complexity, virtue ethics, and wisdom. Copyright 2020 Island Conservation All Rights Reserved.
Gillian manages Revive & Restores incoming grants and outgoing awards to the research community. Location: SF Club Office She is the Executive Director of Revive & Restore, with a missionto enhance biodiversity through the genetic rescue of endangered and extinct species. She co-directs the Paleogenomics Lab at UCSC, and her lab published the first DNA sequences of the Passenger Pigeon in 2002. Revive & Restore is looking for a Communications Director who can give a compelling voice to our conservation story. Ryan is a serial entrepreneur active in both the for-profit and non-profit worlds. Barnaby Marsh serves as a strategist for some of the worlds most ambitious philanthropic projects. We're sequencing that right now at Harvard, with an intern that we're helping to fund, named Ben Novak. The implications for endangered species are tremendous. Besides earning a National Book Award in 1972, the Catalog and its later philanthropy became one of the founding pillars of the Modern Environmental Movementas chronicled in the book Counterculture Green: The Whole Earth Catalog and American Environmentalism (2007 by Andrew Kirk), and in the feature film Earth Days (2009 by Robert Stone). She has organized landmark workshops on genetic rescue bringing together global experts to identify the challenges facing endangered species to identify what genetic tools can be used or designed to help save them from extinction. That begs a question. Acteon and Gambier Archipelagos, French Polynesia. on genetic rescue bringing together global experts to identify the challenges facing endangered species to identify what genetic tools can be used or designed to help save them from extinction. Somebody has to responsibly help the industry and academia think through these heady issues, and I think we're going to start that dialogue this fall. Bens mission in leading the Great Passenger Pigeon Comeback is to set the standard for de-extinction protocols and considerations in the lab and field. aims to maximize the marine benefits of island conservation for ecosystems including coral reefs, and climate and community resilience. [12], "Meet Elizabeth Ann, the First Cloned Black-Footed Ferret", "32-Year-Old DNA Used to Clone Endangered Ferret Species", "Scientists Cloned the Most Endangered Horse in the WorldFrom 40-Year-Old DNA", "Cloning animals by somatic cell nuclear transfer biological factors", "Interspecies Somatic Cell Nuclear Transfer: Advancements and Problems", "We Might Soon Resurrect Extinct Species. To be in favor of human-induced extinction seems one of the pillars of myopia. This is genome engineering, and there may be way too much of a concern over what happens when they go into the wild. No sweat, no grime, nothing muddy, or involving the messy interactions with poor peoples and their politics and economics that characterize my world. Revive & Restore is looking for a Communications Director who can give a compelling voice to our conservation story. We already have captive-bred tigers, but that hasn't stopped the habitat fragmentation and human takeover that has led to fewer than 3500 wild tigers (there were 100,000 in 1900) today in India. Her current work develops techniques to recover and analyze increasingly trace amounts of DNA, such as from environmental and forensic samples. (Admittedly the response might be different in the case of the saber-toothed cat, for instance, which went extinct not long after the invention of farming.) That's quite common in cloning anything. Ben J. Novak collaboratively pioneers new tools for genetic rescue and de-extinction. Gillian works with the Executive Director and Operations Manager to monitor the incoming grants to Revive & Restore, create and monitor budgets, and generate financial statements. Based in the Department of Bioengineering, where she is also an Adjunct Professor, she works closely with groups across the university and with stakeholders in academia, government, industry and civil society around the world.
The most recent, Intended Consequences, took place in June of 2020 which led her to the main stage of TED in Monterey 2021 with her TED Talk titled The Intended Consequences of Helping Nature Thrive and the podcast on TED Radio Hour. Where do we put them? Ben is working with collaborators and partners towards restoring the ecology of the Passenger Pigeon to eastern North American forests. She is on the council of the Engineering Biology Research Consortium (EBRC) and advises a number of organizations on their approaches to the responsible development of biotechnology, including serving on the Board of Revive & Restore. I don't think it's really nature's way. Dr. Beth Shapiro is an evolutionary biologist who specializes in the genetics of ice age animals and plants. The Pyrenean ibex will, one day, need a home, if efforts to resurrect it succeed. An entity does not simply live in its context; it has "context" inside (and on) itself. He later trained in Paleogenomics at the McMaster University Ancient DNA Centre in Ontario (2010-2012). Before joining our team, Marmee owned and operated a restaurant in San Francisco and then Berkeley for 13 years before moving into wine sales. The difference is that now we have much greater awareness of our impact on the world. Specifically, around the study of extinct species we're going to probably learn what made them vulnerable to extinction. Ben graduated from Montana State University studying Ecology and Evolution (2008). We're in the process of starting a new organization. Commits to restoring ____ islands by 2030 with their communities, national, regional, and global partners. Sign up to get our newsletter in your inbox every Wednesday. From 2017 to 2019, Ben worked at the Australian Center for Disease Preparedness CSIRO (Commonwealth Scientific and Industrial Research Organisation) to advance genetic engineering protocols for the domestic pigeon. in Quaternary research from the University of Maine. We don't really know why things go extinct. The Spanish scientists that did all that work feel that that cloning is completely viable. Go deeper into fascinating topics with original video series from TED. [4] The cells had been frozen for 32 years from deceased black-footed ferret named "Willa". Phelan earned her bachelor's degree from the University of California, Berkeley. Id like my cabrito with an apricot-mustard marinade, please. The group was incubated by the Long Now Foundation and co-founded by Stewart Brand and Ryan Phelan in 2012 [1] with the idea of advancing the science of de-extinction of the passenger pigeon, the heath hen,[2] and the woolly mammoth.
Megan has led numerous programs on the role of synthetic biology in society. DMKs content became the backbone of WebMDs consumer health site. The leading national forum open to all for the impartial discussion of public issues important to the membership, community and nation. in Mechanical Engineering from Worcester Polytechnic Institute. The idea of bringing cutting-edge biotech to conservation first went public with Stewarts 2013 TED Talk, The Dawn of De-extinction. Stewart has been an ardent conservationist since he was 10. In 2005 Phelan launched DNA Direct, the first medical genetics company to focus on bringing personalized medicine to the consumer market. Bens work at Revive & Restore also includes extensive education and outreach, the co-convening of seminal workshops, and helping to develop ongoing projects and scope new opportunities to expand genetic rescue science and applications through Revive & Restores Catalyst Science Fund and Wild Genomes Grants. The company was acquired in 2010 by Medco Health Solutions (with over 55 million Medco members) to provide pharmacogenetic testing services and clinical support focused on drug/gene interactions. She also spent 5 years directing policy efforts for the multi-university Synthetic Biology Engineering Research Center (Synberc), and held positions as a project scientist at UC Berkeley, and a postdoctoral scholar at Stanford. Before joining Revive and Restore, Pete developed and led advanced technology development programs of consequence to conservation and climate change. That's why I think an organization like Revive and Restore can actually help with the public discourse. Even among pigeons, there are some learned behaviors. San Francisco, CA 941194210, Copyright 2022 The Commonwealth Club of California | Statement of Values. These audacious projects also advance the use of biotechnology for the genetic rescue of existing endangered species, such as Revive & Restores newest project: the endangered black-footed ferret.
But could it be someday? We're using the term "resurgence" because as you can imagine, there's a lot of controversy over if you could bring back an extinct species, is it invasive? TED.com translations are made possible by volunteer JB ]. Those threatened by invasive diseases may be able to acquire genetic disease resistance. She works collaboratively with the program managers to coordinate and manage the request for proposals, the review process on research awards, payment scheduling, and budget maintenance. He has a long-term interest in using the tools of biotechnology for conservation and environmental issues. The most recent, , took place in June of 2020 which led her to the main stage of TED in Monterey 2021 with her, The Intended Consequences of Helping Nature Thrive, Ryan is a serial entrepreneur, active in the for-profit and non-profit worlds. In addition to Ambion, he also founded Asuragen, a molecular diagnostics company and Mirna Therapeutics, a cancer therapeutics company. Right now, George's approach of basically editing the genome starts to make the concept of bringing something back really plausible. The truth is that when they did that ibex, it only lasted seven minutes, because of a particular lung frailty. But, hopefully, in the fall we'll learn more about that. The ISLAND-OCEAN CONNECTION CHALLENGE aims to maximize the marine benefits of island conservation for ecosystems including coral reefs, and climate and community resilience. We're bringing in 25 to 35 the scientists from all over the world that are actually doing extinction work from the Korean team that's working on the wooly mammoth, to the New Zealand and Australian teams that are de-extincting some species yet to be identified.
That's how resurgence will occur. Stewart Brand, Co-founder, Revive and Restore; Founder, The Long Now Foundation; Founder/Editor, The Whole Earth Catalogue There are different theories about what it is. And if it's nature's way, who in the world says anyone should go about changing nature's way? The goal of Revive & Restore's projects is to enhance biodiversity through new techniques of genetic rescue. The truth is all of this could someday be possible. Jurassic Park fantasies of reclaiming extinct, even long-extinct species appear from time-to-time. Notes from Session 5 of TEDMonterey. This position can be done remotely or on a hybrid schedule if local to the Bay Area. Ben uses his training in ecology and ancient-DNA lab work to contribute, hands-on, to the sequencing of the extinct Passenger Pigeon genome and to study important aspects of its natural history. To the question of who is Ryan Phelan, or anybody else, to bring an extinct species back I would counter: who was anyone to make these animals extinct to begin with? It's another to actually release it into the wild. Here are some commitment examples to inspire your thinking. Open Translation Project.
Ryan works with some of the worlds leading molecular biologists, conservation biologists, and conservation organizations to develop pioneering genetic rescue projects. Someone will say no worries, mate, lets keep their DNA put them back in the wild later. To which the reply is where?. Commits to prioritizing $____ in bi- and multilateral funding to advance these projects.
The most interesting part of all this is going to be where the science goes, what we learn from doing this. Should we? The Commonwealth Club of California is the nation's oldest and largest public affairs forum. Is it "nature's way?" The truth is, if anything happened with that bird, we know it's a tremendous game bird that people loved, and probably people would be shooting it for good meat, good game. Ryan currently serves on the Board of Directors of the Personal Genome Project, which aims to sequence and publicize the complete genomes and medical records of 100,000 volunteers, in order to enable research into personalized medicine. It turns out, of course, that in George's lab he's pioneering in all these methods. Since the inception of Revive & Restore in 2012, Ryan has brought together diverse groups of scientists and conservation practitioners in a series of meetings and workshops to advance the field of genetic rescue. This segment of TED Radio Hour was produced by Katie Monteleone and edited by Sanaz Meshkinpour. There are a couple of broader points of context worth noting. Previously, Megan was a Senior Research Scholar at the Center for International Security and Cooperation (CISAC), part of FSI, where she is now an affiliate. Tom has a B. S. in Zooarchaeology from the University of Florida and an M.S. She currently serves on the Board of Directors of the Personal Genome Project, which aims to sequence and publicize the complete genomes and medical records of 100,000 volunteers in order to enable research into personalized medicine. We just don't have it. Ryan Phelan is a serial entrepreneur active in both the for-profit and non-profit worlds. For the official job description and directions for applying, please click here. We are looking for someone who can help us change the current conservation narrative from one based on fear to one filled with thoughtfully planned, Previously, Megan was a Senior Research Scholar at the. This position represents an exciting opportunity to bring innovative genomic solutions to both long-standing and novel conservation needs. That is just something that cloning technology has to deal with, so he feels really confident if he had funding he could clone an extinct species now without a problem, and solve the lung issue. The Whole Earth Catalog, which he created and ran from 1968 to 1984, purveyed a biological perspective on everything. Ryan Phelan leverages advanced biotechnology solutions to empower conservation efforts. conservation translocations: Over a century of intended consequences, Revive & Restores Heath Hen Event in July 2014, Center for International Security and Cooperation (CISAC). As lead scientist, he heads Revive & Restores de-extinction efforts and is the lead coordinator for conservation cloning projects, and in 2022 has expanded his role to include Program Manager for the newly launched Biotechnology for Bird Conservation endeavor. NOTE: The following conversation took place at the seventh annual. While at DARPA, Bridget was responsible for driving high-risk, high-reward research and development initiatives in synthetic biology, aimed at promoting the use of green technologies to solve big problems. I'm going to just take the passenger pigeon as an example, not because it's my favorite bird, but because it's so iconic. Ryan Phelan is the Co-founder and Executive Director of, Ryan works with some of the worlds leading molecular biologists, conservation biologists, and conservation organizations to envision and develop pioneering genetic rescue projects using cutting-edge genomic technologies to solve seemingly intractable wildlife conservation challenges such as those posed by inbreeding, exotic diseases, climate change, and destructive invasive species. It's going to be about what we learn. This year SB7.0 is brought to you by BioBricks Foundation and SynBioBeta and hosted by the National University of Singapore. To arrive at the edge of the world's knowledge, seek out the most complex and sophisticated minds, put them in a room together, and have them ask each other the questions they are asking themselves. [ ED. For three decades, she played a key role as a nonprofit leader in patient-oriented health care and built two innovative health care companies focused on empowering the health care consumer. They actually were able to get some cellular matter from the last remaining ibex to clone. REALITY CLUB: Jennifer Jacquet, Stuart Pimm, Esther Dyson, [ ED. We'll be talking about the ethics of re-wilding. But what is a genome edited songbird brought back from extinction to do against the poachers in the Mediterranean? There are right now probably three different methods that are being used to contemplate bringing back species. Everyone wants to bring up the Neanderthals, and interestingly enough, anyone who's working around the Neanderthal genome is reluctant to participate in our fall workshop, because they last thing they want is to be criticized or implicated in bringing back a Neanderthal. How do I know this? Just like everything that we know that's really innovative in science, you never know the unintended benefits or what the outcomes are going to be. 16 / Spring 2022 - Climate Geopolitics, No. Time: 5:30 p.m. check-in, 6 p.m. program Well, we recently were at the California Academy of Sciences, up front and personal with Monarch, the last California grizzly, a beautiful specimen there, and we were joking, and not really joking, saying, "Well, what if you could genome edit the California grizzly so that it didn't like the taste of people?" The first of these was the 2013 TedXDeExtinction meeting, which explored the idea of reviving extinct species and re-introducing them to the wild. God knows, it had a tremendous impact. Endangered species that have lost their crucial genetic diversity may be restored to reproductive health.
I think that the extinction that we've seen since man is 99.9 percent caused by man. [3] Afterwards the group's work has expanded to bring back genetic diversity through the cloning of historic, cryopreserved cell lines. Homeschooled until college, he did independent ornithological research as a student at Harvard, Cornell, and Oxford, and did postdoctoral research on complexity and risk at the Max Planck Institute, Berlin, the Hebrew University, Jerusalem, and the Institute for Advanced Study, Princeton. He holds a Ph.D. It's Boston local news in one concise, fun and informative email. The only reason that this concept of bringing back an extinct species works right now is if you can take those genomes and actually edit them based on either a close living relative, or you've got viable cell tissue, and we don't have that. Not shying away from the gargantuan challenges of de-extinction, the organization is pushing forward an endeavor to recreate the woolly mammoth in order to generate ecosystem changes capable of altering adverse climate change on a global scale. Should the entire group have been queried, my guess is that its majority, certainly in the case of the large, delicate, and vegetarian Steller's sea cow, would have answered in a resounding "No." The most traditional is what they refer to as back breeding, and we see that going on right now with the ancient cattle called aurochs. Real scientists those wearing white lab coats using fancy machines with nobs and digital readouts are saving the planet from the excesses of technology. Tom grew up hearing first-hand accounts of the heath hen and as child fantasized he might one day find them in a hidden corner of the Vineyard. Revive & Restore works with some of the worlds leading molecular biologists, conservation biologists, and conservation organizations to develop pioneering, proof-of-concept genetic rescue projects using cutting-edge genomic technologies to solve previously intractable wildlife conservation challenges such as those posed by inbreeding, exotic diseases, climate change, and destructive invasive species. The truth is, we're not. Or does it necessitate more work on pollution, habitat loss, and human behavior because the species that would be the usual victims now have a shot at immortality? She leads social responsibility for the international Genetically Engineered Machine (iGEM) competition, and founded and serves as Executive Director of the Synthetic Biology Leadership Excellence Accelerator Program (LEAP).
degree in Genetics and a Ph.D. in Zoology from the University of California at Berkeley. We don't really know what it is. In various capacities, he has guided more than $3 billion in various non-profit activities and currently specializes in helping philanthropists with capstone benefactions and setting up new private foundations. in Engineering Chemistry from Queens University. Dr. Megan J. Palmer is the Executive Director of Bio Policy & Leadership Initiatives at Stanford University. One, resurrecting a species assumes that there is such a thing as a speciesor a river, for that matter. Prior to joining Revive & Restore Gillian managed the Office of Graduate Studies at Sonoma State University. Biotech entrepreneur Ryan Phelan explores how genetic engineering tools can save species that would otherwise go extinct. You can follow us on Twitter @TEDRadioHour and email us at TEDRadio@npr.org. Brand, founder of the Whole Earth Catalogue, was trained as a biologist at Stanford and served as an infantry officer in the US Army.